Tadact 20 mg contains the active ingredient tadalafil and is primarily used to treat erectile dysfunction (ED) in men. Like other medications in the same class (PDE5 inhibitors), Tadact works by enhancing the effects of nitric oxide, a natural chemical in the body that relaxes smooth muscles in the penis, allowing for increased blood flow and erection when sexually stimulated.

Sexual stimulation is necessary for Tadact 20 mg to work effectively because the medication does not directly cause an erection on its own. Instead, it facilitates the body’s natural response to sexual arousal by enhancing the erectile response to sexual stimulation.

When a man is sexually stimulated, the release of nitric oxide from nerve endings and endothelial cells in the penis triggers the production of cyclic guanosine monophosphate (cGMP). This compound relaxes smooth muscle cells in the blood vessels of the penis, allowing blood to flow in and produce an erection.

Tadact 20 mg works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which breaks down cGMP. By inhibiting PDE5, Tadact helps to maintain higher levels of cGMP in the penis, leading to prolonged smooth muscle relaxation and improved blood flow, which ultimately results in an erection when sexual stimulation occurs.

Without sexual stimulation, the natural biochemical processes that lead to erection activation and the release of nitric oxide do not occur, and therefore, Tadact 20 mg will not be effective in producing an erection. Sexual stimulation is essential to initiate the cascade of events that lead to an erection, even when taking medications like Tadact.